Me Vs Gout

day 3 post flare up update.

Inflammation completely gone, no pain in big toe and full range of motion restored.

6 week clock to do uric acid testing started.
 
Might make a lot of sense to increase your reta dose as long as you can manage to eat enough. We’re still lacking exact data on exactly how much effect to expect but reta is in the ballpark of allopurinol for reducing uric acid (tirz and sema do not have the same effect) and it’s a dose dependent glucagon mediated effect. So unless you need to be there to avoid side effects or starving yourself, using the least effective dose is probably not doing you any big favors.
 
I know this is a peptide forum, but as someone who has defveloped gout in my ankles, let me be a voice of reason. It has been the better part of 8 years without a single flare up and no lifestyle changes since I started taking 100mg Allopurinol. I was born with fucked up liver and horseshoe kidney. That, compounded with congenital heart defects, I see the doctor pretty frequently and have bloodwork done regularly. from what I have experienced, it is best practice to start low and titrate up wth Allopurinol.
 
RetaRX said:


I appreciate everyone’s input. I’m not trying to tell people to not take allo, I’m simply expressing my choice and reasoning.

My wording around long term damage wasn’t the best. I didn’t mean long term usage caused liver and kidney disease, I meant it can cause long term damage. Is it rare? Yes.

I’ve resigned to the fact that if all else fails I will get on Allo or equivalent.

For the time being I’ll give you updates whilst on this adventure 😀✌️

Click to expand...
🚨 🚨 💡 💡 ‼️‼️‼️🔌🔌🔌

Man.... I really hope you hear this because you're arguing against a point no one is making and your science experiment is literally causing you harm.

Everyone keeps trying to explain the same thing, and you keep coming back to inflammation.

‼️‼️ Gout IS NOT an inflammation disease.‼️ ‼️

IT IS a uric acid crystal disease that causes inflammation.

No question that d
iet and weight loss can certainly help lower uric acid, but for most.... ESPECIALLY someone with attacks every 6–8 weeks at age 45..... genetics play a HUGE role, and lifestyle changes alone will NEVER be enough to dissolve those crystals or to get uric acid low enough that more won't form.

You can spend years finding the world's best anti-inflammatory peptide, but if it doesn't lower uric acid enough, or dissolve the crystals (which peptides don't) .... you've treated the smoke while the fire keeps burning.

That's why people keep bringing up allopurinol (or other urate lowering therapies) . They're not saying, "Don't experiment." They're saying, "Don't confuse treating the inflammation with treating the disease.

Experiment all you want for symptom control. Just don't mistake symptom control for disease control which is what you're doing. Both can, and should exist together.
 
Jfrick11 said:


🚨 🚨 💡 💡 ‼️‼️‼️🔌🔌🔌

Man.... I really hope you hear this because you're arguing against a point no one is making and your science experiment is literally causing you harm.

Everyone keeps trying to explain the same thing, and you keep coming back to inflammation.

‼️‼️ Gout IS NOT an inflammation disease.‼️ ‼️

IT IS a uric acid crystal disease that causes inflammation.

No question that d
iet and weight loss can certainly help lower uric acid, but for most.... ESPECIALLY someone with attacks every 6–8 weeks at age 45..... genetics play a HUGE role, and lifestyle changes alone will NEVER be enough to dissolve those crystals or to get uric acid low enough that more won't form.

You can spend years finding the world's best anti-inflammatory peptide, but if it doesn't lower uric acid enough, or dissolve the crystals (which peptides don't) .... you've treated the smoke while the fire keeps burning.

That's why people keep bringing up allopurinol (or other urate lowering therapies) . They're not saying, "Don't experiment." They're saying, "Don't confuse treating the inflammation with treating the disease.

Experiment all you want for symptom control. Just don't mistake symptom control for disease control which is what you're doing. Both can, and should exist together.

Click to expand...

This is 100% accurate.

It is the accumulation of these damn uric acid crystals in the joints that cause the inflammation.
 
RetaRX said:


day 3 post flare up update.

Inflammation completely gone, no pain in big toe and full range of motion restored.

6 week clock to do uric acid testing started.

Click to expand...
So I don't know anything about gout and am asking out of curiosity cause I don't have a dog in this fight; if at 6 weeks, the uric acid comes back wrong, that means you still have gout even without flareups? And if that's a yes, does that mean you'll resign yourself to the allopurinol so it doesn't mess you up just without symptoms?
 
Jfrick11 said:


🚨 🚨 💡 💡 ‼️‼️‼️🔌🔌🔌

Man.... I really hope you hear this because you're arguing against a point no one is making and your science experiment is literally causing you harm.

Everyone keeps trying to explain the same thing, and you keep coming back to inflammation.

‼️‼️ Gout IS NOT an inflammation disease.‼️ ‼️

IT IS a uric acid crystal disease that causes inflammation.

No question that d
iet and weight loss can certainly help lower uric acid, but for most.... ESPECIALLY someone with attacks every 6–8 weeks at age 45..... genetics play a HUGE role, and lifestyle changes alone will NEVER be enough to dissolve those crystals or to get uric acid low enough that more won't form.

You can spend years finding the world's best anti-inflammatory peptide, but if it doesn't lower uric acid enough, or dissolve the crystals (which peptides don't) .... you've treated the smoke while the fire keeps burning.

That's why people keep bringing up allopurinol (or other urate lowering therapies) . They're not saying, "Don't experiment." They're saying, "Don't confuse treating the inflammation with treating the disease.

Experiment all you want for symptom control. Just don't mistake symptom control for disease control which is what you're doing. Both can, and should exist together.

Click to expand...
Thank you for your input. I’m hoping to trial different approaches towards reducing inflammation and uric acid before I commit to a forever medicine. Doesn’t mean others shouldn’t and that I won’t eventually. At this point I don’t want to.

randompersonrandom said:


So I don't know anything about gout and will am asking out of curiosity cause I don't have a dog in this fight; if at 6 weeks, the uric acid comes back wrong, that means you still have gout even without flareups? And if that's a yes, does that mean you'll resign yourself to the allopurinol so it doesn't mess you up just without symptoms?

Click to expand...
Yes, most likely.

Stace_wow said:


What’s your diet like?

Click to expand...
Whole foods high in protein and almost zero alcohol. To be fair, the quality of foods has always been great however volume was probably my biggest problem but that’s under control now.
 
when something in my system goes wonky, I always always look at my diet first….

I had a year long gout flair….and cut meat out….i was better within a week. Not everyone can do this, and of course it may not work for everyone but if problems persist…maybe worth a shot! 😊
 
When evaluating your diet, don't overlook the benefits of coffee. 6 or more cups per day should lower uric acid by 0.4 mg/dl. And it also protects your liver.
 
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