NAD+

T

trey915

New member
Joined
Aug 20, 2026
Messages
37
Reaction score
0
Location
Imported archive
I’m titrating up on NAD+ injections. I see the protocol is for 100-300mcg for loading daily then 2-3x per week and then once each week to once every 2 weeks. But, I’m currently at 80mcg and it burns or in pep speak it’s extremely spicy. For anyone else doing NAD+ suba at those dosages how are you either dealing with the spice or reducing it? I’m currently reconstituting at 100mg/ml. In a couple of days I’ll be increasing to 100 units from my current 80 and eventually to 200 units at that concentration. I googled it and one site recommends mixing a small amount of lidocaine. Thoughts?
 
If your mix is 100mg/ml and your doing 80 units.

Isn't that 80 MG not ug?? I haven't tried it yet, but thought you would start at 5 MG, then 25, on up. 80 mg off the rip seems like it would be spicy.
 
I've been taking it for a while so I may have become used to it. I mix it 500mg/mL and take 20-22 units. I barely feel sting anymore. If I take more than about 110mg in a day, I split it to 100mg/hr.
 
25mg from the start for a week to get used to it, then a loading phase.

For dilution I'm at 100mg/ml (500mg in 5ml vial), just pin it slowly.
 
trey915 said:


I’m titrating up on NAD+ injections. I see the protocol is for 100-300mcg for loading daily then 2-3x per week and then once each week to once every 2 weeks. But, I’m currently at 80mcg and it burns or in pep speak it’s extremely spicy. For anyone else doing NAD+ suba at those dosages how are you either dealing with the spice or reducing it? I’m currently reconstituting at 100mg/ml. In a couple of days I’ll be increasing to 100 units from my current 80 and eventually to 200 units at that concentration. I googled it and one site recommends mixing a small amount of lidocaine. Thoughts?

Click to expand...
Click to expand...
Be sure to know the difference from mcg and mg.

1000 mcg=1mg

1000 mg= 1 gram

As for the burn, I have done several NAD+ cycles and just added sufficient BAC.

I did 100mg daily (m-f) for 6 weeks 5 on 2 off

EDIT

yes i did 500mg/5ml and injections were 100mg/1ml
 
I'm starting today with a 25mg dose to see how I react. I've gotten a 150mg injection from a Wellness clinic with no issue before but this will be my first time self administering the injection and it has been a while.
 
Shaqdiesel said:


I'm starting today with a 25mg dose to see how I react. I've gotten a 150mg injection from a Wellness clinic with no issue before but this will be my first time self administering the injection and it has been a while.

Click to expand...
Click to expand...

I did 25mg every day for a week and now doing 25mg 3-4x/week. I tried 50mg for a week and had a couple uncomfortable flushing reactions (face warm to the touch, sort of tingly feeling) so backed it back down to 25mg and staying there. It is the only peptide besides reta I felt on day one.
 
I remember when I started that it burned. I switched to the thigh which seemed to help. Now I inject 115 units without a thought. Give it some time, should get better.
 
Glenn said:


I remember when I started that it burned. I switched to the thigh which seemed to help. Now I inject 115 units without a thought. Give it some time, should get better.

Click to expand...
Click to expand...
Are you using two syringes? 100 units and then 15 units? Maybe me but such an odd dose?
 
Is your NAD+ buffered or no? I recon a 500mg vial of buffered NAD+ with NaCl BAC and its not spicy at all for me. YMMV, cause a lot of spicy peps apparently do nothing to me.
 
Specifying units without mg/ml context means nothing, I see a lot of people doing that.

I am doing the 14 week mitochondrial repair protocol.

Started at 25mg, then 50mg, then 100mg.

To reduce the sting, I started with 500mg/10ml so 50 units=25mg and 100 units=50mg.

I now mix 500mg/5ml so 100 units=100 mg.

See how only talking in units can be confusing when we have no idea how much BAC?

I hope it's not 500mg/1ml, does that even mix properly?

Only taking 100mcg is also confusing.
 
I am also doing the mito protocol. On the second week of ss31 currently. I recon my NAD+ at 200mg/ml. So that is 2.5ml of BAC for a 500mg vial of NAD+. Twice a week I do a shot of 50 units to give me my 100mgs each.
 
CNCCurrency said:


I get that, why such an odd dose?

Click to expand...
Click to expand...
That’s the syringes I have on hand and the concentration I have made up. I think my next vile, I will double the concentration and then inject 150mg.
 
I also mix at 200mg/ml as I like to limit my pins to 50 units. I get a little burn but it goes away in a minute. Spiciness is definitely YMMV.
 
trey915 said:


I’m titrating up on NAD+ injections. I see the protocol is for 100-300mcg for loading daily then 2-3x per week and then once each week to once every 2 weeks. But, I’m currently at 80mcg and it burns or in pep speak it’s extremely spicy. For anyone else doing NAD+ suba at those dosages how are you either dealing with the spice or reducing it? I’m currently reconstituting at 100mg/ml. In a couple of days I’ll be increasing to 100 units from my current 80 and eventually to 200 units at that concentration. I googled it and one site recommends mixing a small amount of lidocaine. Thoughts?

Click to expand...
Click to expand...
NaD+ peptocol subq should be somewhere between 50mg and 100 mg roughly. Not micrograms. Everyone is different. I never felt the burn at 50-75mg but I get a head rush. First time I gave my husband a 100mg subq shot he said it burned so I took him back down to 75mg. That’s the sweet spot for both of us. Just find that sweet spot which is the lowest dose effective dose for YOU. Good luck
 
javajoe316 said:


If your mix is 100mg/ml and your doing 80 units.

Isn't that 80 MG not ug?? I haven't tried it yet, but thought you would start at 5 MG, then 25, on up. 80 mg off the rip seems like it would be spicy.

Click to expand...
Click to expand...
It is 80mg. The recommended is 100-300mg. I started lower and have moved up.
 
ktg123 said:


I've been taking it for a while so I may have become used to it. I mix it 500mg/mL and take 20-22 units. I barely feel sting anymore. If I take more than about 110mg in a day, I split it to 100mg/hr.

Click to expand...
Click to expand...
So you just got accustomed to it?
 
Back
Top